Invention Grant
- Patent Title: Immunoproteasome inhibitor analogs
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Application No.: US16078348Application Date: 2017-03-10
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Publication No.: US10584105B2Publication Date: 2020-03-10
- Inventor: Michael C. Pirrung , Nicole A. Bakas , Andre Bachmann
- Applicant: The Regents of the University of California , Board of Trustees of Michigan State University
- Applicant Address: US CA Oakland US MI East Lansing
- Assignee: The Regents of the University of California,Board of Trustees of the Michigan State University
- Current Assignee: The Regents of the University of California,Board of Trustees of the Michigan State University
- Current Assignee Address: US CA Oakland US MI East Lansing
- Agency: Gavrilovich, Dodd & Lindsey LLP
- International Application: PCT/US2017/021931 WO 20170310
- International Announcement: WO2017/156471 WO 20170914
- Main IPC: C07D281/00
- IPC: C07D281/00 ; C07D285/00 ; C07D417/12 ; A61K45/06 ; C07K5/062 ; A61P35/00 ; A61K9/00 ; A61K31/395 ; A61K31/497
Abstract:
The disclosure provides for compounds having immunoproteasome inhibitory activity, and pharmaceutical compositions made thereof. The disclosure further provides for the use of the compounds and compositions in treating various diseases and disorders in a subject that are associated with immunoproteasome activity, including inflammatory disorders, autoimmune disorders, hematological disorders, and neurodegenerative disorders.
Public/Granted literature
- US20190047969A1 IMMUNOPROTEASOME INHIBITOR ANALOGS Public/Granted day:2019-02-14
Information query
