Provided is a multilayer-structure circular knit fabric that has excellent cool touch sensation and moisture absorbability, has improved moisture dispersibility, is quick drying to avoid the feeling of dampness, is very comfortable with high cool touch sensation, can reduce stickiness and a cold feeling after sweating by causing the sweat to dry quickly, and has a pleasant texture. The multilayer-structure circular knit fabric is formed of a single circular knit having a layer structure with two or more layers, and has a section where a cellulose-based continuous fiber and a hydrophobic fiber form the same knit loop.