A method, computer program product, and system for selective memory mirroring including identifying, by a computer during an initial program load, predictively deconfigured memory units and memory interfaces, wherein the predictively deconfigured memory units and memory interfaces are marked by the computer for removal from a computer configuration prior to the initial program load, analyzing the predictively deconfigured memory units and memory interfaces to determine a level of granularity for selective memory mirroring and initiating selective memory mirroring at the determined level of granularity using the analyzed predictively deconfigured memory units and memory interfaces.