Decision support technology is provided for use with patients who may experience respiratory deterioration. A mechanism is provided to determine whether a patient is experiencing (or is likely to experience at a future time) an autoimmune inflammatory event, which may include performing a spectral analysis on a time series of nocturnal or axillary temperatures for the patient to determine a spectrum slope or intercept. The time series may be demeaned, detrended, and apodized before performing the spectral analysis. A comparison of the slope or intercept with a baseline value is used to determine an indication of the patient's likely condition or future condition regarding the autoimmune inflammatory event. Based on the comparison, an intervening action may be invoked, such as alerting a caregiver, providing a recommendation or modified treatment, or determining and recommending a tailored prescription of medicine for the patient.