Invention Grant
- Patent Title: Pharmaceutical composition comprising sacubitril and valsartan
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Application No.: US16046531Application Date: 2018-07-26
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Publication No.: US10588892B2Publication Date: 2020-03-17
- Inventor: Bohumil Dymacek , Marta Vivancos Martinez , Luis Nogueiras Nieto , Lisardo Alvarez Fernandez , Rohit Kumar , Jose Velada Calzada , Petr Mitas
- Applicant: Synthon B.V.
- Applicant Address: NL Nijmegen
- Assignee: SYNTHON B.V.
- Current Assignee: SYNTHON B.V.
- Current Assignee Address: NL Nijmegen
- Agency: Buscher Patent PLLC
- Priority: EP17183859 20170728
- Main IPC: A61K31/41
- IPC: A61K31/41 ; A61K9/20 ; A61K31/225 ; A61K9/00 ; A61K9/28 ; A61K31/216 ; C07D257/04
Abstract:
The present invention relates to a pharmaceutical composition comprising a physical mixture of sacubitril sodium and valsartan disodium, wherein the X-ray powder diffraction pattern of valsartan disodium comprises characteristic peaks at the following 2 theta (±0.2) angles: 4.70°, 9.29°, 22.34°, measured using a Cu Kα radiation. The invention further relates to the use of said pharmaceutical composition as medicament in the treatment of heart failure.
Public/Granted literature
- US20190030000A1 PHARMACEUTICAL COMPOSITION COMPRISING SACUBITRIL AND VALSARTAN Public/Granted day:2019-01-31
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