Invention Grant
- Patent Title: Recurrent gene fusions in cutaneous CD30-positive lymphoproliferative disorders
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Application No.: US15547325Application Date: 2016-01-29
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Publication No.: US10590488B2Publication Date: 2020-03-17
- Inventor: Kojo Elenitoba-Johnson , Mark J. Kiel , Delphine Rolland , Bryan L. Betz , Nathanael G. Bailey , Thirunavukkarasu Velusamy , Megan Lim
- Applicant: The Regents of the University of Michigan
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casmir Jones, SC
- Agent Robert A. Goetz
- International Application: PCT/US2016/015714 WO 20160129
- International Announcement: WO2016/123517 WO 20160804
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12Q1/68 ; C12Q1/6886 ; C12Q1/686
Abstract:
Provided herein are kits, compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to recurrent gene fusions (e.g., recurrent translocations involving TYK2) as diagnostic markers and clinical targets for cutaneous CD30-positive lymphoproliferative disorders (e.g., lymphomatoid papulosis; primary cutaneous anaplastic large cell lymphoma).
Public/Granted literature
- US20180010196A1 RECURRENT GENE FUSIONS IN CUTANEOUS CD30-POSITIVE LYMPHOPROLIFERATIVE DISORDERS Public/Granted day:2018-01-11
Information query
