Invention Grant
- Patent Title: Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
-
Application No.: US13830871Application Date: 2013-03-14
-
Publication No.: US10591391B2Publication Date: 2020-03-17
- Inventor: Roland Stoughton , Ravi Kapur , Barb Ariel Cohen , Daniel Shoemaker , Ronald W. Davis , Mehmet Toner
- Applicant: Verinata Health, Inc. , The General Hospital Corporation , GPB Scientific, LLC
- Applicant Address: US CA Redwood City US MA Boston US VA Richmond
- Assignee: Verinata Health, Inc.,The General Hospital Corporation,GPB Scientific, LLC
- Current Assignee: Verinata Health, Inc.,The General Hospital Corporation,GPB Scientific, LLC
- Current Assignee Address: US CA Redwood City US MA Boston US VA Richmond
- Agency: Fish & Richardson P.C.
- Main IPC: G01N1/30
- IPC: G01N1/30 ; C12Q1/6883 ; G16B20/00
Abstract:
The present invention provides systems, apparatuses, and methods to detect the presence of fetal cells when mixed with a population of maternal cells in a sample and to test fetal abnormalities, i.e. aneuploidy. In addition, the present invention provides methods to determine when there are insufficient fetal cells for a determination and report a non-informative case. The present invention involves quantifying regions of genomic DNA from a mixed sample. More particularly the invention involves quantifying DNA polymorphisms from the mixed sample.
Public/Granted literature
- US20130280709A1 DIAGNOSIS OF FETAL ABNORMALITIES USING POLYMORPHISMS INCLUDING SHORT TANDEM REPEATS Public/Granted day:2013-10-24
Information query
