According to at least one example embodiment, a multi-chip system includes multiple chip devices configured to communicate to each other and share resources, such as I/O devices. According to at least one example embodiment, a method of synchronizing access to an input/output (I/O) device in the multi-chip system comprises initiating, by a first agent of the multi-chip system, a first operation for accessing the I/O device, the first operation is queued, prior to execution by the I/O device, in a queue. Once the first operation is queued, an indication of such queuing is provided. Upon detecting, by a second agent of the multi-chip system, the indication of queuing the first operation in the queue, initiating a second operation to access the I/O device, the second operation is queued subsequent to the first operation in the queue.