Invention Grant
- Patent Title: Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders
-
Application No.: US15613847Application Date: 2017-06-05
-
Publication No.: US10596116B2Publication Date: 2020-03-24
- Inventor: Wenbin Lin , Demin Liu , Joseph Della Rocca , Stephanie Kramer , Christopher Y. Poon
- Applicant: The University of North Carolina at Chapel Hill
- Applicant Address: US NC Chapel Hill
- Assignee: The University of North Carolina at Chapel Hill
- Current Assignee: The University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61K9/127 ; A61K47/69 ; A61K9/14 ; A61K9/00 ; A61K9/51 ; A61P19/10 ; A61P19/08 ; A61K47/54 ; A61P35/00 ; A61K31/663 ; A61K31/675 ; A61K49/00 ; A61K51/12

Abstract:
Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e.g., bone-resorption-related diseases, osteoporosis, Paget's disease, and bone metastases) and as imaging agents.
Public/Granted literature
- US20170333347A1 METAL BISPHOSPHONATE NANOPARTICLES FOR ANTI-CANCER THERAPY AND IMAGING AND FOR TREATING BONE DISORDERS Public/Granted day:2017-11-23
Information query