- Patent Title: Method and process for quantitative evaluation of pharmacokinetics, therapeutic effects and safety of delivery of drug compounds to the inner ear for treatment of auditory disease
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Application No.: US15631933Application Date: 2017-06-23
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Publication No.: US10596267B2Publication Date: 2020-03-24
- Inventor: Jeffrey T. Borenstein , Erin Pararas , Ernest S. Kim , Vishal Tandon , Andrew Ayoob , Michael McKenna , William Sewell , Marcello Peppi , Marc Weinberg , Robert Langer
- Applicant: The Charles Stark Draper Laboratory, Inc. , Massachusetts Eye and Ear Infirmary , Massachusetts Institute of Technology
- Applicant Address: US MA Cambridge US MA Boston US MA Cambridge
- Assignee: The Charles Stark Draper Laboratory, Inc.,Massachusetts Eye and Ear Infirmary,Massachusetts Institute of Technology
- Current Assignee: The Charles Stark Draper Laboratory, Inc.,Massachusetts Eye and Ear Infirmary,Massachusetts Institute of Technology
- Current Assignee Address: US MA Cambridge US MA Boston US MA Cambridge
- Agency: Foley & Lardner LLP
- Agent Christopher J. McKenna
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K9/06 ; A61K47/10 ; A61K47/60 ; A61K31/498
Abstract:
The present disclosure provides compositions and methods for treating an auditory disease in a subject in need thereof comprising administering an effective amount of a gel-based precursor that includes an inner ear-specific therapeutic compound directly into the cochlea of the subject.
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