A method and apparatus to neutralize or destroy pathogens in red blood cell concentrate (RBCC). The apparatus may include a lamp to provide ultra-violet (UV) light having a predetermined wavelength, a focusing member to focus the UV light from the lamp, a chamber assembly to receive the RBCC at a predetermined flow rate and to cause the received RBCC to be exposed to the focused UV light, and a controller. The chamber assembly may include a window and a bladder assembly. The bladder assembly may have a movable bladder portion. The controller may control movement of the bladder portion such that a space provided between the window and a surface of the bladder assembly, wherein the RBCC is caused to flow, enables the focused UV light to neutralize or destroy at least some of the pathogens in the RBCC during flow through the space.