An object of the present invention is to provide a vehicle body structure with improved rigidity of a vehicle body. The vehicle body structure includes a side sill extending in a vehicle front-rear direction and having at least a side sill inner member, a side sill reinforcing member disposed outside in a vehicle width direction of the side sill inner member at a rear portion of the side sill inner member, and a wheel arch member disposed behind the side sill, wherein the side sill reinforcing member includes a first fixing portion fixed to an outer surface of the wheel arch member from the outside in the vehicle width direction, and a second fixing portion fixed to a front surface of the wheel arch member from the front.