Invention Grant
- Patent Title: Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof
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Application No.: US15950683Application Date: 2018-04-11
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Publication No.: US10597367B2Publication Date: 2020-03-24
- Inventor: Nicholas David Peter Cosford , Dhanya Raveendra-Panickar , Douglas J. Sheffler , John Howard Hutchinson , Reto Andreas Gadient
- Applicant: Sanford Burnham Prebys Medical Discovery Institute
- Applicant Address: US CA La Jolla
- Assignee: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
- Current Assignee: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
- Current Assignee Address: US CA La Jolla
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: C07D243/12
- IPC: C07D243/12 ; A61K31/551 ; A61P25/00 ; C07D243/14 ; A61K31/4196 ; A61K31/426 ; A61K31/427 ; A61K31/433 ; C07D217/06 ; C07D417/04 ; C07D249/08 ; C07D277/20 ; C07D285/08 ; C07D403/12 ; C07D233/54 ; C07D401/04 ; C07D401/10 ; C07D401/12 ; C07D403/10 ; C07D405/04 ; C07D239/26 ; C07D409/04 ; C07D271/06 ; C07D275/02 ; C07D277/30 ; A61K31/505 ; A61K31/506 ; C07D231/12 ; C07D233/64 ; C07D261/08 ; C07D263/32 ; C07D277/26 ; C07D307/38 ; C07D333/24 ; C07D401/14 ; C07D405/10 ; C07D409/02 ; C07D409/14 ; C07D413/04 ; C07D413/14 ; C07D417/10 ; C07D417/14
Abstract:
Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor negative allosteric modulators (NAMs), compositions comprising the compounds, and methods of using the compounds and compositions.
Public/Granted literature
- US20190016715A1 METABOTROPIC GLUTAMATE RECEPTOR NEGATIVE ALLOSTERIC MODULATORS (NAMS) AND USES THEREOF Public/Granted day:2019-01-17
Information query
