Invention Grant
- Patent Title: Prodrug of 1,1′-(1,6-dioxo-1,6-hexanediyl)bis-D-proline
-
Application No.: US15837297Application Date: 2017-12-11
-
Publication No.: US10597385B2Publication Date: 2020-03-24
- Inventor: Alexis Denis , Olivier Mirguet , Jérôme Toum
- Applicant: GlaxoSmithKline Intellectual Property Development Limited
- Applicant Address: GB Brentford, Middlesex
- Assignee: GlaxoSmithKline Intellectual Property Development Limited
- Current Assignee: GlaxoSmithKline Intellectual Property Development Limited
- Current Assignee Address: GB Brentford, Middlesex
- Agent Robert J. Smith
- Priority: GB1407506.3 20140429
- Main IPC: A61K31/4025
- IPC: A61K31/4025 ; C07D405/14 ; A61K9/00 ; A61K39/395 ; A61K39/00
Abstract:
The present invention relates to the compound (2R,2′R)-bis(((((tetrahydro-2H-pyran-4-yl)oxy)carbonyl)oxy)methyl) 1,1′-adipoylbis(pyrrolidine-2-carboxylate), pharmaceutical compositions comprising the same and the use of the same for treatment of diseases or disorders wherein depletion of serum amyloid P component (SAP) would be beneficial, including amyloidosis, Alzheimer's disease, type 2 diabetes mellitus and osteoarthritis.
Public/Granted literature
- US20180099955A1 PRODRUG OF 1,1'-(1,6-DIOXO-1,6-HEXANEDIYL)BIS-D-PROLINE Public/Granted day:2018-04-12
Information query
IPC分类:
