An interlock system for use in a wellbore and method of using same, including a plurality of sensors configured to detect physical conditions within a wellbore. The sensors may be absolute locational sensors or relative locational sensors. Electronic signals are generated when sensors detect corresponding physical conditions. A processor derives location information from the electronic signals, and verifies location by comparison to pre-programmed reference information for each sensor. A trigger signal is generated when at least two location information have been verified, which is used to activate a downhole event. A timer may also be set with a calculated time delay before the trigger signal is generated. The interlock system operates independent of connection to any device at the surface of a wellbore, and may be attached to any equipment for deployment down a wellbore.