Examples described herein involve determining an audio processing algorithm for a playback device to apply when playing audio content in a playback zone. Determining the audio processing algorithm may involve causing the playback device to play a first audio signal in the playback zone, receiving data indicating a second audio signal detected by a microphone of the playback device. Based on the second audio signal and a characteristic of the playback device, an audio processing algorithm may be determined. The audio processing algorithm may be calculated, or identified in a database based on an acoustic characteristic of the playback zone. The acoustic characteristic of the playback zone may be determined based on the second audio signal and the characteristic of the playback device. The audio processing algorithm may then be applied by the playback device.