Example methods and systems to validate integrity of data and one or more configurations in response to an upgrade in a virtualized computing environment are disclosed. One method may include preparing a first pre-upgrade backup file and a first post-upgrade backup file in response to a data plane upgrade of the virtualized computing environment and validating the integrity of data and one or more configurations based on the first pre-upgrade backup file and the first post-upgrade backup file before upgrading a control plane of the virtualized computing environment.