Efficient breakpoint detections via caches comprises monitoring a memory location by detecting cache misses on a cache. Embodiments include identifying a memory address that is to be monitored, storing the memory address in a breakpoint monitoring list, and ensuring that any cache lines overlapping with the memory address are evicted from a cache. Based at least on an indication of an occurrence of a cache miss, embodiments determine whether a portion of a cache line imported into the cache based on the cache miss overlaps with the memory address stored in the breakpoint monitoring list. When the portion of the imported cache line does overlap with the memory address, embodiments process one or more monitoring operations on the memory address, and, based on the memory address being stored in the breakpoint monitoring list, embodiments evict the imported cache line from the cache.