Techniques are described for iteratively adjusting data processing decision results in accordance with rules. In some implementations, the applied rules may be data ethics rules associated with particular demographic groups, such as users in a particular geographic location, users in a particular age range, and so forth. The rules may describe the manner in which data, such as data that describes or identifies individuals, is collected, stored, analyzed, applied, manipulated, and/or destroyed. The various stages of data handling may be described as a data supply chain, and a set of rules may apply to the handling of data at one or more stages of the data supply chain. The rules may enforce data privacy considerations and/or other types of constraints on data handling.