Invention Grant
- Patent Title: System and methods for identifying a base call included in a target sequence
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Application No.: US15953087Application Date: 2018-04-13
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Publication No.: US10600501B2Publication Date: 2020-03-24
- Inventor: Tongbin Li , Wuming Gong , Jiang Rao
- Applicant: AccuraScience, LLC
- Agent Zheng “Andy” Liu
- Main IPC: G16B30/00
- IPC: G16B30/00 ; G16B20/00 ; G16B40/00

Abstract:
Base calls for a target sequence may be identified relative to a reference sequence by using values from sequencing reads at locations satisfying a high-confidence condition to identify base calls at a given location not satisfying the high-confidence condition. The high-confidence condition may relate to the level of coverage by the sequencing reads at a location of the reference sequence. The quality of measurements of the sequencing reads may be incorporated into the base-call process.
Public/Granted literature
- US20180232485A1 METHOD AND APPARATUS FOR CALLING SINGLE-NUCLEOTIDE VARIATIONS AND OTHER VARIATIONS Public/Granted day:2018-08-16
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