A speaker system with a thermoelectric conversion device includes a basin frame and a vibration system and a magnetic circuit system that are accommodated in the basin frame. The vibration system includes a diaphragm and a voice coil. The magnetic circuit system includes a T-iron, a magnet and a washer, with a magnetic gap between the washer and the magnet and the T-iron. The voice coil moves up and down in the magnetic gap. A thermoelectric conversion device is connected to the speaker including a thermoelectric power generation module, a boost circuit module, and a load management module. The thermoelectric power generation module is fixedly connected to a back surface of the T-iron for thermoelectric power generation. The boost circuit module boosts and regulates a direct current outputted by the thermoelectric power generation module. The load management module performs a power distribution and load management on the boosted new power.