Invention Grant
- Patent Title: Lipids that increase insulin sensitivity and methods of using the same
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Application No.: US14775399Application Date: 2014-03-14
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Publication No.: US10604473B2Publication Date: 2020-03-31
- Inventor: Barbara B. Kahn , Mark A. Herman , Alan Saghatelian , Edwin Homan
- Applicant: Beth Israel Deaconess Medical Center, Inc. , President and Fellows of Harvard College
- Applicant Address: US MA Boston US MA Cambridge
- Assignee: Beth Israel Deaconess Medical Center, Inc.,President and Fellows of Harvard College
- Current Assignee: Beth Israel Deaconess Medical Center, Inc.,President and Fellows of Harvard College
- Current Assignee Address: US MA Boston US MA Cambridge
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- International Application: PCT/US2014/029329 WO 20140314
- International Announcement: WO2014/144777 WO 20140918
- Main IPC: C07C69/22
- IPC: C07C69/22 ; G01N33/92 ; C07D495/04 ; G01N33/53

Abstract:
The invention provides, inter alia, fatty acyl hydroxy fatty acid (FAHFA; a novel class of estolide-related molecules) and diagnostic and treatment methods for a variety of disorders—including diabetes-related disorders, Metabolic Syndrome, polycystic ovarian syndrome, cancer, and inflammatory disorders—using them; as well as methods of screening for additional compounds that are useful in treating these disorders and/or that modulate FAHFA levels, FAHFA-mediated signaling, and FAHFA-mediated biological effects.
Public/Granted literature
- US20160221925A1 Lipids That Increase Insulin Sensitivity And Methods Of Using The Same Public/Granted day:2016-08-04
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