Invention Grant
- Patent Title: Thyroid stimulating hormone receptor peptides and uses thereof
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Application No.: US15537577Application Date: 2015-12-23
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Publication No.: US10646589B2Publication Date: 2020-05-12
- Inventor: Lotta Jansson , Keith Martin , David Wraith , Andrea Jahraus , Kathleen Vrolix
- Applicant: APITOPE INTERNATIONAL NV
- Applicant Address: BE Diepenbeek
- Assignee: APITOPE INTERNATIONAL NV
- Current Assignee: APITOPE INTERNATIONAL NV
- Current Assignee Address: BE Diepenbeek
- Agency: Marshall, Gerstein & Borun LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@7adfa456 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@1a8406e3 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@467d1bd6 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@54447e85
- International Application: PCT/IB2015/059942 WO 20151223
- International Announcement: WO2016/103213 WO 20160630
- Main IPC: A61K38/04
- IPC: A61K38/04 ; C07K5/00 ; C07K7/00 ; C07K16/00 ; C07K17/00 ; A61K48/00 ; A61K39/00 ; C07K14/72 ; A01K67/027 ; A61K38/17 ; A61P5/14
Abstract:
The present invention provides a composition which comprises the following Thyroid Stimulating Hormone Receptor (TSHR) peptides: (i) all or part of the amino acid sequence KKKKYVSIDVTLQQLESHKKK (SEQ ID NO: 1), or a part thereof, or a sequence having at least 60% sequence identity to SEQ ID NO:1; and (ii) all or part of the amino acid sequence GLKMFPDLTKVYSTD (SEQ ID NO: 2), or a part thereof, or a sequence having at least 60% sequence identity to SEQ ID NO:2. The present invention also relates to the use of such a composition for the prevention or suppression of activating autoantibody formation in Graves' disease.
Public/Granted literature
- US20180264139A1 COMPOSITION Public/Granted day:2018-09-20
Information query
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