Invention Grant
- Patent Title: Aldose reductase inhibitors and methods of use thereof
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Application No.: US16182169Application Date: 2018-11-06
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Publication No.: US10647726B2Publication Date: 2020-05-12
- Inventor: Andrew Wasmuth , Donald W. Landry
- Applicant: The Trustees of Columbia University in the City of New York
- Applicant Address: US NY New York
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee Address: US NY New York
- Agency: Wilmer Cutler Pickering Hale and Dorr LLP
- Main IPC: C07D495/04
- IPC: C07D495/04 ; A61P9/10 ; A61P25/02 ; A61P17/00 ; A61P13/12
Abstract:
The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, the treatment of ischemic injury, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention. Other disorders can include, but are not limited to, atherosclerosis, coronary artery disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy, diabetic cardiomyopathy, infections of the skin, peripheral vascular disease, stroke, asthma, and the like.
Public/Granted literature
- US20190300543A1 ALDOSE REDUCTASE INHIBITORS AND METHODS OF USE THEREOF Public/Granted day:2019-10-03
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