Invention Grant
- Patent Title: Reducing nonsense-mediated mRNA decay
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Application No.: US14916561Application Date: 2014-09-04
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Publication No.: US10647983B2Publication Date: 2020-05-12
- Inventor: Adrian Krainer , Isabel Aznarez , Tomoki Nomakuchi
- Applicant: Cold Spring Harbor Laboratory
- Applicant Address: US NY Cold Spring Harbor
- Assignee: Cold Spring Harbor Laboratory
- Current Assignee: Cold Spring Harbor Laboratory
- Current Assignee Address: US NY Cold Spring Harbor
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2014/054151 WO 20140904
- International Announcement: WO2015/035091 WO 20150312
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K31/713 ; C12Q1/6883 ; A61K31/4245 ; A61K31/726 ; C07H21/02
Abstract:
The present disclosure relates to compositions and methods for inhibiting nonsense-mediated mRNA decay in a gene-specific manner, for example in the treatment of diseases or disorders caused by nonsense mutations.
Public/Granted literature
- US20170159049A9 REDUCING NONSENSE-MEDIATED MRNA DECAY Public/Granted day:2017-06-08
Information query
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