Invention Grant
- Patent Title: Approach for treating inflammatory disorders
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Application No.: US16079588Application Date: 2017-02-24
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Publication No.: US10647987B2Publication Date: 2020-05-12
- Inventor: Frank Jaschinski , Ksenija Schirduan , Sven Michel
- Applicant: Secarna Pharmaceuticals GmbH & Co. KG
- Applicant Address: DE Marburg
- Assignee: Secama Pharmaceuticals GmbH & Co KG
- Current Assignee: Secama Pharmaceuticals GmbH & Co KG
- Current Assignee Address: DE Marburg
- Agency: BakerHostetler
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@441c45f6 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@58eeea05
- International Application: PCT/EP2017/054374 WO 20170224
- International Announcement: WO2017/144685 WO 20170831
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/11 ; C07H21/02 ; C07H21/04 ; C12N15/113 ; A61P25/28 ; A61P29/00 ; A61P35/00
Abstract:
The present invention relates to a novel approach for treating inflammatory disorders and other diseases, which is based on targeting ROR gamma t mRNA. The invention is directed to oligonucleotides comprising 10 to 22 modified or unmodified nucleotides complementary to specifically selected regions of the RORC, transcript variant 2 mRNA (RORC2), which codes for the ROR gamma t protein.
Public/Granted literature
- US20190055566A1 NOVEL APPROACH FOR TREATING INFLAMMATORY DISORDERS Public/Granted day:2019-02-21
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