An environment control system and a method of guiding occupant to make demand response to environment status thereof are provided. The system includes an external apparatus, a wireless apparatus, a control host and an electronic apparatus. The external apparatus adjusts an environmental status, and the wireless apparatus broadcasts a trigger message in a wireless network. The electronic apparatus outputs a feedback notification after receiving the trigger message, generates corresponding feedback data, and transfers the feedback data to the control host. The control host receives a plurality of the feedback data from the electronic apparatus and executes a statistic analysis process for obtaining analysis data. The present disclosed example has ability of making people with stronger intention in response to environment status and improving accuracy of the responses via actively giving notice for assisting people in instant feedback when people are in the environment.