Techniques are described herein that are capable of performing sound source localization (SSL) confidence estimation using machine learning. An SSL operation is performed with regard to a sound to determine an SSL direction estimate and an SSL-based confidence associated with the SSL direction estimate based at least in part on a multi-channel representation of the sound. The SSL direction estimate indicates an estimated direction from which the sound is received. The SSL-based confidence indicates an estimated probability that the sound is received from the estimated direction. The multi-channel representation includes representations of the sound that are detected by respective sensors (e.g., microphones). Additional characteristic(s) of the sound are automatically determined. A machine learning (ML) operation is performed based at least in part on the SSL direction estimate, the SSL-based confidence, and the additional characteristic(s) to determine an ML-based confidence associated with the SSL direction estimate.