A virtual switching method, a related apparatus, and a computer system are provided. The method includes the Host configures virtual environment between a source node and a target node in combination with an agent module, receiving a first message sent by a source node, where the first message is used to request a first virtual machine to perform switching processing on to-be-switched data, where the to-be-switched data is sent from the source node to a target node and at least one of the source node and the target node is a second virtual machine; and determining a second message according to an address of the target node contained in the to-be-switched data and a configured port mapping table, and sending the second message, where the second message is used to instruct the target node to acquire the to-be-switched data from a storage device of a hardware layer.