The present disclosure discloses an OLED display panel, including a TFT array substrate and a plurality of anodes disposed in an array on the TFT array substrate, the TFT array substrate has a pixel defining layer disposed thereon, the pixel defining layer includes opening portions and spacing portions, and each opening portion corresponds to one sub-pixel area; wherein, the pixel defining layer has a first common layer, a second common layer and a cathode layer sequentially disposed thereon, and a light emitting material is disposed between the first common layer and the second common layer corresponding to each sub-pixel area; wherein, a hole blocking portion is further disposed above the spacing portion, and the hole blocking portion spaces the first common layer between two adjacent sub-pixel areas. The present disclosure further discloses a method for manufacturing the OLED display panel as mentioned above.