A thermal control system for controlling a temperature of a fluid delivered to a patient is provided. The thermal control system includes a cavity that removably receives a cartridge housing the fluid. The thermal control system includes a heat exchanger in thermal contact with at least one of the opposing walls of the cavity. The cartridge includes opposing surfaces defining a chamber therebetween for housing the fluid, the cartridge adapted to be removably received within the cavity. A biasing element is incorporated into the cartridge and adapted to bias the opposing cartridge surfaces away from one another and into contact with the opposing cavity walls. Contact between the cartridge surfaces and the cavity walls facilitates the transfer of thermal energy between the heat exchanger and the fluid housed within the cartridge.