Invention Grant
- Patent Title: Treatment of impulsivity-related disorders
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Application No.: US16097239Application Date: 2017-04-27
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Publication No.: US10653680B2Publication Date: 2020-05-19
- Inventor: Robert David Rogers , Trevor Sharp
- Applicant: OXFORD UNIVERSITY INNOVATION LIMITED
- Applicant Address: GB Botley, Oxford
- Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
- Current Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
- Current Assignee Address: GB Botley, Oxford
- Agency: Liang & Hennessey LLP
- Agent Stanley D. Liang
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@5d53bc6f
- International Application: PCT/GB2017/051174 WO 20170427
- International Announcement: WO2017/187176 WO 20171102
- Main IPC: A61K31/41
- IPC: A61K31/41 ; A61K31/428 ; A61K45/06 ; A61P25/34 ; A61P25/36 ; A61P25/32 ; A61P25/16 ; A61K9/00

Abstract:
The invention relates to the treatment of impulsivity-related disorders, such as a substance-related addiction, a behavioural addiction, relapse to a substance-related or behavioural addiction, a habit or impulsive disorder, an emotional unstable personality disorder, intentional self harm, an eating disorder, a dopamine agonist-induced impulse control disorder, or attention deficit hyperactivity disorder (ADHD) by administering a compound of Formula I or a salt thereof to a subject; Formula (I) wherein: E is S or Se; R1 and R2 are optional substituents, and are at each occurrence independently selected from: (1) a halogen, which is preferably selected from F, CI and Br; (2) C1-C4 alkyl, such as C1-C2 alkyl or C1 alkyl, optionally substituted with one or more halogen atoms, each of which is preferably selected from F, CI and Br; and (3) C1-C4 alkoxy, such as C1-C2 alkoxy or C1 alkoxy; optionally substituted with one or more halogen atoms, each of which is preferably selected from F, CI and Br; m is an integer in the range of from 0 to 5; and n is an integer in the range of from 0 to 4. The compound can also be used to treat or control impulsivity control disorders in patients undergoing dopamine agonist treatment, for example in patients suffering from Parkinson's disease or ADFID.
Public/Granted literature
- US20190111029A1 TREATMENT OF IMPULSIVITY-RELATED DISORDERS Public/Granted day:2019-04-18
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