Invention Grant
- Patent Title: Oxadiazoles and thiadiazoles as TGF-β inhibitors
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Application No.: US16172312Application Date: 2018-10-26
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Publication No.: US10653682B2Publication Date: 2020-05-19
- Inventor: Mark J. Suto , Vandana V. Gupta , Bini Mathew , Joanne Murphy-Ullrich
- Applicant: Southern Research Institute , UAB Research Foundation
- Applicant Address: US AL Birmingham US AL Birmingham
- Assignee: Southern Research Institute,UAB Research Foundation
- Current Assignee: Southern Research Institute,UAB Research Foundation
- Current Assignee Address: US AL Birmingham US AL Birmingham
- Agency: Ballard Spahr LLP
- Main IPC: A61K31/433
- IPC: A61K31/433 ; A61K31/4245 ; A61P37/06 ; A61K31/4709 ; A61P35/00 ; A61K31/4439
Abstract:
The present disclosure is concerned with oxadiazole and thiadiazole analogs that are capable of inhibiting TGF-β and methods of treating cancers such as, for example, multiple myeloma and a hematologic malignancy, and methods of treating fibrotic conditions using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Public/Granted literature
- US20190125730A1 OXADIAZOLES AND THIADIAZOLES AS TGF-BETA INHIBITORS Public/Granted day:2019-05-02
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