Invention Grant
- Patent Title: PRMT5 inhibitors and uses thereof
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Application No.: US15501550Application Date: 2015-08-04
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Publication No.: US10653693B2Publication Date: 2020-05-19
- Inventor: Kenneth W. Duncan , Richard Chesworth , Paula Ann Boriack-Sjodin , Michael John Munchhof , Lei Jin , Elayne Penebre , Olena I. Barbash
- Applicant: Epizyme, Inc. , Glaxosmithkline Intellectual Property Development Limited
- Applicant Address: US MA Cambridge GB Brentford, Middlesex
- Assignee: Epizyme, Inc.,Glaxosmithkline Intellectual Property Development Limited
- Current Assignee: Epizyme, Inc.,Glaxosmithkline Intellectual Property Development Limited
- Current Assignee Address: US MA Cambridge GB Brentford, Middlesex
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2015/043679 WO 20150804
- International Announcement: WO2016/022605 WO 20160211
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/4725 ; A61K31/513 ; A61P35/00 ; A61K45/06 ; G01N33/574
Abstract:
Described herein are methods of treating cancer using one or more PRMT5 inhibitors, for example using one or more compounds of Formulae (1-5) or (A-F), pharmaceutically acceptable salts thereof, and/or pharmaceutical compositions thereof. Described herein are methods of treating cancer using one or more PRMT5 inhibitors, for example using one or more compounds of Formulae (1-5) or (A-F), pharmaceutically acceptable salts thereof, and/or pharmaceutical compositions thereof.
Public/Granted literature
- US20170224685A1 PRMT5 INHIBITORS AND USES THEREOF Public/Granted day:2017-08-10
Information query
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