- Patent Title: Oligonucleotide-based probes for detection of bacterial nucleases
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Application No.: US15430217Application Date: 2017-02-10
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Publication No.: US10653800B2Publication Date: 2020-05-19
- Inventor: James O. McNamara, II , Katie R. Flenker , Lingyan Huang , Alexander R. Horswill , Mark A. Behlke , Frank J. Hernandez
- Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION , INTEGRATED DNA TECHNOLOGIES, INC.
- Applicant Address: US IA Iowa City US IA Coralville
- Assignee: University of Iowa Research Foundation,Integrated DNA Technologies, Inc.
- Current Assignee: University of Iowa Research Foundation,Integrated DNA Technologies, Inc.
- Current Assignee Address: US IA Iowa City US IA Coralville
- Agency: Viksnins Harris Padys Malen LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/00 ; C12P19/34 ; A61K49/00 ; G01N33/569 ; C12Q1/44 ; G01N33/542 ; C12Q1/689 ; C12Q1/6818 ; C12Q1/6823
Abstract:
The present invention relates to a rapid detection of microbial-associated nuclease activity with chemically modified nuclease (e.g., ribonuclease) substrates, and probes and compositions useful in detection assays.
Public/Granted literature
- US20170224847A1 OLIGONUCLEOTIDE-BASED PROBES FOR DETECTION OF BACTERIAL NUCLEASES Public/Granted day:2017-08-10
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