Invention Grant
- Patent Title: Bicyclic hydroxamic acids useful as inhibitors of mammalian histone deacetylase activity
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Application No.: US16063682Application Date: 2016-11-16
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Publication No.: US10654814B2Publication Date: 2020-05-19
- Inventor: Kristin Hammer , Mattias Jönsson , Lars Krüger
- Applicant: KANCERA AB
- Applicant Address: SE
- Assignee: KANCERA AB
- Current Assignee: KANCERA AB
- Current Assignee Address: SE
- Agency: Adsero IP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@7642a1b6
- International Application: PCT/EP2016/077914 WO 20161116
- International Announcement: WO2017/108282 WO 20170629
- Main IPC: C07D263/54
- IPC: C07D263/54 ; C07D277/66 ; C07D307/79 ; C07D333/54 ; C07D413/04 ; C07D413/10 ; C07D413/14 ; C07D417/04 ; C07D471/04 ; C07D495/04 ; C07D498/04 ; A61K31/57 ; C07D401/04 ; C07D263/57 ; C07D263/58 ; C07D209/08 ; C07D409/04 ; C07D491/04 ; C07D235/30 ; C07D487/04 ; C07D277/64 ; C07D413/12

Abstract:
A compound of formula (Ia) or (Ib) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of a histone deacetylase, and as such is useful in therapy, e.g. in the treatment of autoimmune disorders, mental disorders, neurodegenerative disorders, and hyperproliferative disorders.
Public/Granted literature
- US20190284147A1 BICYCLIC HYDROXAMIC ACIDS USEFUL AS INHIBITORS OF MAMMALIAN HISTONE DEACETYLASE ACTIVITY Public/Granted day:2019-09-19
Information query