Invention Grant
- Patent Title: Urea compound and preparation method and application thereof
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Application No.: US16474003Application Date: 2017-12-27
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Publication No.: US10654815B2Publication Date: 2020-05-19
- Inventor: Qianjiao Yang , Xianping Lu , Zhibin Li , Lijun Xin , Yonglian Song , Chao Fu
- Applicant: SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD.
- Applicant Address: CN Shenzhen, Guangdong
- Assignee: SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD.
- Current Assignee: SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD.
- Current Assignee Address: CN Shenzhen, Guangdong
- Agency: Apex Attorneys at Law, LLP
- Agent Yue (Robert) Xu
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@64d668a8
- International Application: PCT/CN2017/118844 WO 20171227
- International Announcement: WO2018/121560 WO 20180705
- Main IPC: C07D265/30
- IPC: C07D265/30 ; C07C275/24 ; C07D405/12 ; C07D413/14

Abstract:
The present invention relates to a urea compound and a preparation method and an application thereof. The structure of the present compound is represented by formula (I), the definition of each variable in the formula being as described in the description. The compound can block interaction between the PD-1/PD-L1 signalling pathways. The compound of the present invention can be used for treating or preventing diseases related to the signalling pathways, such as cancer, autoimmune disease, chronic infectious disease, and other diseases.
Public/Granted literature
- US20190337906A1 UREA COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF Public/Granted day:2019-11-07
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