Invention Grant
- Patent Title: Pyrimidine derivative, method for preparing same and use thereof in medicine
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Application No.: US16302310Application Date: 2017-05-19
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Publication No.: US10654836B2Publication Date: 2020-05-19
- Inventor: Lei Chen , Dongliang Guan , Hua Bai , Jun Gou , Weifeng Zhao , Zhongli Wang , Long Ling , Yutao Ma
- Applicant: Zhejiang Hisun Pharmaceutical Co., Ltd.
- Applicant Address: CN
- Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
- Current Assignee: Zhejiang Hisun Pharmaceutical Co., Ltd.
- Current Assignee Address: CN
- Agency: Lerner, David, Littenberg, Krumholz & Mentlik, LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@4884d80f
- International Application: PCT/CN2017/085135 WO 20170519
- International Announcement: WO2017/198221 WO 20171123
- Main IPC: C07D403/14
- IPC: C07D403/14 ; C07D403/12 ; C07D471/10 ; C07D487/10 ; A61K31/506 ; A61P35/00 ; C07D403/04

Abstract:
The present invention relates to a pyrimidine derivative, a method for preparing same and use thereof in medicine. In particular, the present invention relates to a pyrimidine derivative represented by general formula (I), a method for preparing same and a pharmaceutically acceptable salt thereof as well as use thereof as a therapeutic agent, in particular as a FGFR4 kinase inhibitor, definitions of each substituent in the general formula (I) being the same as those defined in the description.
Public/Granted literature
- US20190161476A1 Pyrimidine Derivative, Method For Preparing Same And Use Thereof In Medicine Public/Granted day:2019-05-30
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