- Patent Title: Aminopyridine compounds useful as inhibitors of protein prenylation
-
Application No.: US15518127Application Date: 2015-10-07
-
Publication No.: US10654838B2Publication Date: 2020-05-19
- Inventor: Marc Peschanski , Sophie Blondel , Xavier Nissan
- Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , ASSOCIATION FRANCAISE CONTRE LES MYOPATHIES , UNIVERSITE D'EVRY VAL D'ESSONNE
- Applicant Address: FR Paris FR Paris FR Evry
- Assignee: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM),ASSOCIATION FRANCAISE CONTRE LES MYOPATHIES,UNIVERSITE D'EVRY VAL D'ESSONNE
- Current Assignee: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM),ASSOCIATION FRANCAISE CONTRE LES MYOPATHIES,UNIVERSITE D'EVRY VAL D'ESSONNE
- Current Assignee Address: FR Paris FR Paris FR Evry
- Agency: Oliff PLC
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@3d059350
- International Application: PCT/EP2015/073141 WO 20151007
- International Announcement: WO2016/055517 WO 20160414
- Main IPC: C07D409/14
- IPC: C07D409/14 ; C07D403/12 ; C07D401/14 ; C07D405/14 ; C07D401/06 ; C07D401/02
Abstract:
A compound for use in the treatment and/or prevention of diseases or disorders wherein an inhibition of protein prenylation is required, which is alternatively chosen among wherein R1 is 2-pyridyl, 3-pyridyl or 4-pyridyl; R2 represents: and wherein R5 and R6 represent a hydrogen atom or a (C1-4)alkyl group; and R7 represents an arylcarbonyl group, a heteroarylcarbonyl group, a heteroarylacetyl group, a (C1-C4)alkoxy-carbonylmethyl group, a group. Also disclosed are novel compounds of formulae (I) and (II).
Public/Granted literature
- US20170305892A1 NOVEL AMINOPYRIDINE COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN PRENYLATION Public/Granted day:2017-10-26
Information query
