- Patent Title: Compositions and methods for the treatment of neuromyelitis optica
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Application No.: US14113061Application Date: 2012-04-23
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Publication No.: US10654916B2Publication Date: 2020-05-19
- Inventor: Jeffrey L. Bennett , Gregory P. Owens , Alan S. Verkman
- Applicant: Jeffrey L. Bennett , Gregory P. Owens , Alan S. Verkman
- Applicant Address: US CA Oakland US CO Denver
- Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION,THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION,THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE
- Current Assignee Address: US CA Oakland US CO Denver
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo PC
- Agent Terri Shieh-Newton; David Dang
- International Application: PCT/US2012/034662 WO 20120423
- International Announcement: WO2012/145746 WO 20121026
- Main IPC: C07K16/18
- IPC: C07K16/18 ; C07K16/28 ; A61K39/395 ; A61K45/06

Abstract:
The present invention is directed to antibodies binding to aquaporin 4 (AQP4) and methods of using such antibodies to treat neuromyelitis optica (NMO) either as a monotherapy or in combination with standard NMO therapies such as immunosuppressives or plasmaphersis.
Public/Granted literature
- US20140170140A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROMYELITIS OPTICA Public/Granted day:2014-06-19
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