Invention Grant
- Patent Title: P2X4 antibodies and uses thereof
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Application No.: US15308294Application Date: 2015-05-02
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Publication No.: US10654926B2Publication Date: 2020-05-19
- Inventor: Wendy A Williams , Clare Jones , James Button , John Linley , Harm Jan Snijder , Ling Huang , Yoko Shibata , Sudharsan Sridharan , Maria Groves , Claire Dobson
- Applicant: MedImmune Limited
- Applicant Address: GB Cambridge
- Assignee: MedImmune Limited
- Current Assignee: MedImmune Limited
- Current Assignee Address: GB Cambridge
- International Application: PCT/EP2015/059633 WO 20150502
- International Announcement: WO2015/166105 WO 20151105
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; A61K39/00
Abstract:
The invention provides antibodies that specifically bind a P2X4 polypeptide and modulate P2X4 channel activity, recombinant P2X4 polypeptides and methods for generating such polypeptides, as well as compositions and methods for generating anti-P2X4 antibodies, and methods of using P2X4 antibodies for the treatment of neuropathic pain and other indications.
Public/Granted literature
- US20170166634A1 ION CHANNEL MODULATORS AND USES THEREOF Public/Granted day:2017-06-15
Information query
