A method includes generating a material landmark images in a low and high energy image domain. The material landmark image estimates a change of a value of an image pixel caused by adding a small amount of a known material to the pixel. The method further includes generating an air values image in the low and high energy image domain. The air values image estimates a value for each image pixel where a value of a pixel is replaced by a value representing air. The method further includes extracting from de-noised low and high images generated from the low and high line integrals, a material composition of each image pixel based on the material landmark images and air values image. The method further includes generating a signal indicative the extracted material composition.