Invention Grant
- Patent Title: Pharmaceutical microemulsion immobilized in a thin polymer matrix and methods of making them
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Application No.: US15105802Application Date: 2014-12-16
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Publication No.: US10660862B2Publication Date: 2020-05-26
- Inventor: Prakash Sapkal , Nidhi Sapkal , Varsha Pokharkar , Lubna Daud
- Applicant: ZIM LABORATORIES LIMITED
- Applicant Address: IN Kalmeshwar
- Assignee: ZIM LABORATORIES LIMITED
- Current Assignee: ZIM LABORATORIES LIMITED
- Current Assignee Address: IN Kalmeshwar
- Agency: Maschoff Brennan
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@2817fe1e
- International Application: PCT/IN2014/000779 WO 20141216
- International Announcement: WO2015/107544 WO 20150723
- Main IPC: A61K9/70
- IPC: A61K9/70 ; A61K38/28 ; A61K9/107 ; A61K9/113 ; A61K38/23 ; A61K38/18 ; A61K38/26 ; A61K38/22 ; A61K38/29 ; A61K38/31 ; A61K31/444 ; A61K31/496 ; A61K31/5415 ; A61K31/196 ; A61K31/403 ; A61K31/216 ; A61K31/64 ; A61K31/445 ; A61K9/00 ; A61K31/4515 ; A61K31/437 ; A61K31/436 ; A61K47/10 ; A61K47/12 ; A61K47/26 ; A61K47/32 ; A61K47/34 ; A61K47/38

Abstract:
The invention comprises a ready to use film dosage form comprising microemulsion of an Active Pharmaceutical Ingredient embedded or immobilized in a thin polymeric matrix as a double microemulsion and a process of making the same. The microemulsion in the film dosage form of this invention is capable of being absorbed through mucosal route. The process of making the film dosage of this invention comprises steps of forming a film forming dispersion containing film forming polymers, excipients and microemulsion of active pharmaceutical ingredient, casting the same in the form of a film and drying the cast of the film being carried out by means of drying conditions that suit to retain stability of the active pharmaceutical ingredient being selected such that drying of the film is achieved retaining the moisture trapped in the microemulsion embedded in the polymeric film.
Public/Granted literature
- US20160317462A1 PHARMACEUTICAL MICROEMULSION IMMOBILIZED IN A THIN POLYMER MATRIX AND METHODS OF MAKING THEM Public/Granted day:2016-11-03
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