Invention Grant
- Patent Title: Method for induction of T cells from pluripotent stem cells
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Application No.: US15526294Application Date: 2015-11-13
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Publication No.: US10660915B2Publication Date: 2020-05-26
- Inventor: Shin Kaneko , Atsutaka Minagawa , Yutaka Yasui
- Applicant: KYOTO UNIVERSITY
- Applicant Address: JP Kyoto-shi, Kyoto
- Assignee: Kyoto University
- Current Assignee: Kyoto University
- Current Assignee Address: JP Kyoto-shi, Kyoto
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@7f9f05d3
- International Application: PCT/JP2015/081959 WO 20151113
- International Announcement: WO2016/076415 WO 20160519
- Main IPC: A61K35/14
- IPC: A61K35/14 ; C12N5/10 ; A61K35/17 ; C12N5/0783 ; C12N5/074 ; C12N5/16 ; C12N5/00
Abstract:
The present invention provides a method for efficiently inducing CD8-positive T cells by adding vitamin C to the medium in the steps of induction of the CD8-positive T cells from pluripotent stem cells. The present invention also provides a method for efficiently inducing CD8-positive T cells by performing culture in a medium supplemented with an adrenocortical hormone agent in the step of induction of the CD8-positive T cells from CD4/CD8 double-positive T cells.
Public/Granted literature
- US20170326175A1 METHOD FOR INDUCTION OF T CELLS FROM PLURIPOTENT STEM CELLS Public/Granted day:2017-11-16
Information query
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