Invention Grant
- Patent Title: Hematopoietic stem cells in combinatorial therapy with immune checkpoint inhibitors against cancer
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Application No.: US15748284Application Date: 2016-07-29
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Publication No.: US10660954B2Publication Date: 2020-05-26
- Inventor: Duane Mitchell , Catherine Flores
- Applicant: University of Florida Research Foundation, Incorporated
- Applicant Address: US FL Gainesville
- Assignee: University of Florida Research Foundation, Incorporated
- Current Assignee: University of Florida Research Foundation, Incorporated
- Current Assignee Address: US FL Gainesville
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2016/044718 WO 20160729
- International Announcement: WO2017/023753 WO 20170209
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; A61K35/28 ; C07K16/28 ; C12N5/00 ; A61P31/12 ; A61P35/00 ; A61K45/06
Abstract:
The novel synergistic combination of immune checkpoint blockade and hematopoietic stem cell transplantation and/or hematopoietic stem cell mobilization yield synergistic effects in disease therapy.
Public/Granted literature
- US20180214544A1 HEMATOPOIETIC STEM CELLS IN COMBINATORIAL THERAPY WITH IMMUNE CHECKPOINT INHIBITORS AGAINST CANCER Public/Granted day:2018-08-02
Information query
