Invention Grant
- Patent Title: Guanidine derivative and medical use thereof
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Application No.: US16317350Application Date: 2017-07-28
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Publication No.: US10662156B2Publication Date: 2020-05-26
- Inventor: Yoshitaka Numajiri , Keiichi Okimura , Yuki Matsumura , Kennunettsu Asaba , Tomohide Masuda , Kazuyuki Tokumaru , Yasufumi Goto , Shigeo Fujii
- Applicant: Toray Industries, Inc.
- Applicant Address: JP Tokyo
- Assignee: Toray Industries, Inc.
- Current Assignee: Toray Industries, Inc.
- Current Assignee Address: JP Tokyo
- Agency: DLA Piper LLP (US)
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@9c58585 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@400c2830
- International Application: PCT/JP2017/027395 WO 20170728
- International Announcement: WO2018/021520 WO 20180201
- Main IPC: C07D213/36
- IPC: C07D213/36 ; C07D213/57 ; C07D401/12 ; C07D405/12 ; C07D409/12 ; C07D417/12 ; C07D213/61 ; C07D213/63 ; C07D239/26 ; A61P37/02 ; A61P17/06 ; A61P37/08 ; A61K31/444 ; A61K31/505 ; A61K31/4418 ; C07D213/84 ; C07D213/81 ; A61P43/00 ; A61K31/4439 ; A61K31/443 ; A61P37/06 ; A61K31/4436
Abstract:
A compound has a guanidine skeleton that inhibits the protease activity of MALT1 and exerts a therapeutic or prophylactic effect on autoimmune disease such as psoriasis or allergic disease such as atopic dermatitis. The guanidine derivative is typified by the following formula or a pharmacologically acceptable salt thereof.
Public/Granted literature
- US20190233376A1 GUANIDINE DERIVATIVE AND MEDICAL USE THEREOF Public/Granted day:2019-08-01
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