Invention Grant
- Patent Title: Compound of 4′-thionucleoside, as well as preparation method therefor, pharmaceutical composition thereof and application thereof
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Application No.: US15558620Application Date: 2016-03-28
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Publication No.: US10662214B2Publication Date: 2020-05-26
- Inventor: Hong Ye , Gang Liu , Nan Yu , Hong Zeng , Mingliang Zhao , Yan Qing , Hua Deng , Wenjia Li , Donghong Li , Donghai Su , Wei Zhong , Shaohua Li , Xunwei Wu , Lichun Wang , Jingyi Wang
- Applicant: Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
- Applicant Address: CN Sichuan
- Assignee: Sichuan Keiun-Biotech Biopharmaceutical Co., Ltd.
- Current Assignee: Sichuan Keiun-Biotech Biopharmaceutical Co., Ltd.
- Current Assignee Address: CN Sichuan
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@164e2c99
- International Application: PCT/CN2016/077519 WO 20160328
- International Announcement: WO2016/155593 WO 20161006
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70 ; C07H19/10 ; C07H19/20 ; C07H1/00 ; A61K31/7068 ; A61K31/7076 ; A61K45/06
Abstract:
The present invention relates to a novel compound of 4′-thionucleoside, a preparation method therefor, a pharmaceutical composition comprising the same and an application thereof. Specifically, the present invention relates to a phosphamide derivative of 4′-thionucleoside, a preparation method therefor, a pharmaceutical composition comprising the same, a use thereof in the preparation of a medicine for preventing or treating abnormal cell proliferation diseases (for example, tumors or cancers and related diseases) or virus infectious diseases, and a method of using the same for preventing or treating abnormal cell proliferation diseases (for example, tumors or cancers and related diseases) or virus infectious diseases.
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