Invention Grant
- Patent Title: Backbone cyclized inhibitory peptides of myeloid differentiation factor 88 (MyD88)
-
Application No.: US16307841Application Date: 2017-06-04
-
Publication No.: US10662225B2Publication Date: 2020-05-26
- Inventor: Gabriel Nussbaum , Amnon Hoffman , Chaim Gilon
- Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
- Applicant Address: IL Jerusalem
- Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
- Current Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
- Current Assignee Address: IL Jerusalem
- Agency: J.A. Lindeman & Co., PLLC
- International Application: PCT/IL2017/050621 WO 20170604
- International Announcement: WO2017/212477 WO 20171214
- Main IPC: C07K7/56
- IPC: C07K7/56 ; A61P21/00 ; A61P35/00 ; A61P25/14 ; A61P37/08 ; A61K38/00
Abstract:
Provided are backbone cyclized peptides that interfere with signaling of the intracellular adaptor protein MyD88. Pharmaceutical compositions including these backbone cyclized peptides as well as their use in treatment of multiple sclerosis (MS) and other diseases associated with MyD88 signaling are also disclosed.
Public/Granted literature
- US20190185516A1 BACKBONE CYCLIZED INHIBITORY PEPTIDES OF MYELOID DIFFERENTIATION FACTOR 88 (MYD88) Public/Granted day:2019-06-20
Information query
