A neural network system for execution of a sum-of-products operation includes a memory device and a controller. The memory device includes a 3D array having a plurality of memory cells with programmable conductances disposed in cross-points of a plurality of cell body lines and gate lines, a gate driver coupled to the gate lines and applying control gate voltages in combination with the programmable conductances for corresponding to weights of terms in the sum-of-products operation, a input driver used to apply voltages to the memory cells corresponding to input variables, a plurality of input lines connecting the cell body lines to the input driver, a sensing circuit used to sense currents passing through the memory cells corresponding the terms in the sum-of-products operation, a buffer circuit used to store the terms. The controller is used to control the memory device summing up the terms in the sum-of-products operation.