Invention Grant
- Patent Title: Treatment of urea cycle disorders in neonates and infants
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Application No.: US16128140Application Date: 2018-09-11
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Publication No.: US10668040B2Publication Date: 2020-06-02
- Inventor: Bruce Scharschmidt , Masoud Mokhtarani
- Applicant: Horizon Therapeutics, LLC
- Applicant Address: US IL Lake Forest
- Assignee: Horizon Therapeutics, LLC
- Current Assignee: Horizon Therapeutics, LLC
- Current Assignee Address: US IL Lake Forest
- Agent Chris Marion
- Main IPC: A61K31/216
- IPC: A61K31/216 ; A61K9/00 ; G01N33/84
Abstract:
Nitrogen scavenging drugs such as glycerol phenylbutyrate can be administered safely to infants and toddlers with urea cycle disorders by adjusting the dosage based on one or more biomarkers selected from the group consisting of urinary-PAGN and plasma PAA:PAGN ratio.
Public/Granted literature
- US20190076386A1 TREATMENT OF UREA CYCLE DISORDERS IN NEONATES AND INFANTS Public/Granted day:2019-03-14
Information query
